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Volume 35: Chlorine, Bromine, and Iodine |
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Introduction by Prof. Ernst Schaumann (Volume Editor): |
Shortly after the publication of Science of Synthesis, Vol. 34 (Fluorine),
this volume now adds the synthesis of chloroalkanes, bromoalkanes, and iodoalkanes and so completes the coverage of the haloorganics.
This is an important class of intermediates, especially for nucleophilic displacement reactions and elimination reactions. Moreover,
there are important applications of haloalkanes in organic materials such as PVC. In addition, halogen substitution is used quite often to
achieve biological activity, as in some biocides, or to fine-tune the performance of a drug.
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