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Volume 21: Three Carbon¾Heteroatom Bonds:
Amides and Derivatives; Peptides; Lactams |
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Introduction by Prof. Steve Weinreb (Volume Editor): |
| This volume is one of seven of Science of Synthesis dealing with compounds with four
and three carbon—heteroatom bonds (Category 3). The volume falls in the latter subcategory,
and covers the synthesis of compounds possessing an amide bond, incorporating
lactams and peptides. A chapter on acyl phosphorus compounds has also been included.
However, it should be noted that amide polymers have not been included, even though
they constitute an important class of amido compounds. This omission is primarily due
to the fact that these macromolecules are not traditional targets for chemists working in
the area of organic synthesis, and a treatment of polymers would not be of value to the
vast majority of readers of Science of Synthesis.
The volume follows the same organization as the other Category 3 volumes of
Science of Synthesis. The material has been organized into methods of synthesis of the
particular product class, usually with a brief discussion of the scope of the method, followed
by specific examples and representative experimental procedures. In general, the
product classes are ordered using the usual Science of Synthesis pattern.
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