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Guide

E22: Synthesis of Peptides and Peptidomimetics

5 English-language volumes

Editor-in-Chief:
Murray Goodman, San Diego, USA

Editors:
Arthur Felix, Mahwah, USA
Luis Moroder, Martinsried, Germany
Claudio Toniolo, Padova, Italy

Houben-Weyl Synthesis of Peptides and Peptidomimetics is to represent the most valuable extract from more than 100 years of peptide synthesis, first reported by Emil Fischer in 1899. In 1974, Houben-Weyl published Synthese von Peptiden edited by Professor Erich Wünsch. This field of chemistry has changed dramatically since then and the new English language volume will reflect the current challenges of a discipline which is at the center of modern chemistry and biology.

The five-volume set, edited by the internationally renowned peptide chemists Professors Murray Goodman, Arthur Felix, Luis Moroder, and Claudio Toniolo will comprise a critical selection of synthetic methods in a consistent style, and will be indispensable for every synthetic chemist.

Synthesis of Peptides (E22a and E22b) includes protecting groups, peptide bond formation, the synthesis of peptides and proteins detailing general and specific methods, and analytical techniques used to determine the structure and composition of peptides.

Synthesis of Peptidomimetics (E22c and E22d) features side and/or main-chain modified peptides, peptides with secondary structure mimetics and inducers, de novo peptide structures, macropeptide structures, and reactive peptides.

Reviewer's comments on E22a:

"...In this first volume, you will find many synthetic gems that you can bring to your own practice of peptide or peptidomimetic chemistry, whether you are new to the field or an old-timer. This is a volume that you will want to explore; once you start you will have trouble putting it down." - Victor J. Hruby, Arizona, USA.

Click here to read an independent review (pdf) of E22a by Dr. John Jones.

Click here for a detailed table of contents (pdf) for volumes E22.

Vol.	Pub. Year	No. of Pages	Price	ISBN (RoW) ISBN (US)
E22a	2002	976	€uro 1850 US$ 2200	3-13-219604-5 1-58890-022-3	order
E22b	2002	785	€uro 1850 US$ 2200	3-13-114424-6 1-58890-023-1	order
E22c	2002	847	€uro 2200 US$ 2640	3-13-125514-5 1-58890-024-X	order
E22d	2003	395	€uro 2200 US$ 2640	3-13-128874-4 1-58890-070-3	order
E22e	2003	497	€uro 1400 US$ 1680	3-13-136394-0 1-58890-182-3	order

For further information or to receive a free Houben-Weyl Users' Guide please contact us.

News

Award for
Eric N. Jacobsen

We would like to congratulate Eric N. Jacobsen, Editorial Board Member, Science of Synthesis, on being awarded the Yamada–Koga Prize 2008 which is awarded every year to a scientist whose research has a major impact in the fields of the synthesis of optically active compounds. The Yamada–Koga Prize will be awarded to Professor Eric N. Jacobsen on November 14, 2008, at the 18th Symposium on Optically Active Compounds held in Tokyo, Japan.

Awards for
Steven V. Ley

We would like to congratulate Steven V. Ley, Editorial Board Member, Science of Synthesis, on receiving the Prous Institute-Overton and Meyer Award for New Technologies in Drug Discovery, European Federation of Medicinal Chemistry, Vienna (2008) and the Hans Heroff Inhoffen Medal, Helmholtz Zentrum für Infectionsforschung (2008).

Professor
John Colin Tatlow
(1923–2008)

We are very sorry to announce that Professor John Colin Tatlow passed away in the UK on April 9th, 2008. Professor Tatlow was the Editor-in-Chief of the E10 Organo-Fluorine Compounds (Houben–Weyl) series and made a major contribution to fluorine chemistry during his career. He was the recipient of the American Chemical Society Award for Creative Work in Fluorine Chemistry in 1990. We would like to extend our sincere condolences to his family and friends.

Over 18,000
New Reactions
Added to

Science of Synthesis
Version 3.5
New York/Stuttgart – Thieme is pleased to announce that Science of Synthesis Version 3.5 is now available. The electronic information resource now contains 34 volumes, out of what will eventually be a total of 48 volumes. This upgraded version has a total of 195,000 reactions, with over 18,000 new reactions, and holds significant synthetic methods for a wide range of classes of compounds. The newly added content consists of volumes 29 and 31

Volume Publication

Science of Synthesis
Volume 37
We are very pleased to announce the publication of Science of Synthesis Volume 37 [Compounds with One Saturated Carbon¾Heteroatom Bond: Ethers] by Craig J. Forsyth and Eric N. Jacobsen in May 2008. The volume is 992 pages in length and provides a critical review of methods for the synthesis of ethers.

Thieme IUPAC Prize

Congratulations to
F. Dean Toste,
recipient of the 2008 Thieme–IUPAC Prize.