Protecting Groups

The Third Edition was published November 22, 2003. In February, 2005, this highly lauded new edition has also been made available as a soft cover. Read E. J. Corey's evaluation of the new edition here.

Features of the Third Edition:

• Focuses on a relatively small number of commonly used protecting groups
• Places emphasis on deprotection conditions
• Uses schemes extensively
• Has been reorganised and thoroughly revised and updated
• Two new chapters on thiol and phosphate protecting groups have been added
• The number of schemes has increased from 500 to 1200
• Colour has been introduced as an aid to visual retrieval
• The number of references has increased from 1200 to 2270 with emphasis given to literature covering the period 1990-2001

Protecting Groups is an invaluable survey of the most widely used protecting groups.

Protecting Groups provides a critical survey of protecting group methodology and focuses on the most widely used protecting groups for the most common functional groups. It provides an essential learning tool for advanced students and professionals in a broad range of disciplines involving organic synthesis.

Protecting Groups is organized by functional group and places special emphasis on deprotection conditions applied to complex structures where selectivity is a key issue. The discussion of each protecting group is divided into three sections beginning with deprotection conditions, followed by methods of formation, and ending with some characteristic NMR data to aid the reader in identifying the contribution from the protecting group. At the end of each chapter is a list of reviews for the topics covered in that chapter.

For independent reviews of the 3rd edition of Protecting Groups, click on the link here.

For an independent review of the 2nd edition of Protecting Groups, click on the link here.