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When conducting a search for patent information I type in the patent code as seen in another
database but I get no hits even though I am sure that this compound appears in
Pharmaceutical Substances. Why?
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In order to search the patent references contained in Pharmaceutical Substances
the patent number has to be entered in a specific format. In Pharmaceutical Substances
each patent reference is entered in three digit groups separated by a space. See below:
AU 9 189 615
DE 70 459
DRP 327 129
EP 33 538
GB 800 635
US 5 159 104
So if you have a five digit code enter the first three numbers, then add a space, and
then enter the final two numbers. We intend to remove the program's sensitivity to
spacing with the next major upgrade in the middle of 2003. |
| How can I find information in Pharmaceutical Substances on patent expiry dates? |
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Pharmaceutical Substances is intended as a reference work that allow the user to
rapidly assess the relevance of a compound for their purposes, and directs the user
to the correct source of information within the primary literature. Hence, it does not
contain comprehensive patent information, expiry data is not included. However, all patent
applications are included, so that when this product is used in conjunction with a patent
database the user can quickly find the information they need. |
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I use Pharmaceutical Substances in conjunction with other references including patent
databases, citation indices, and reference works on synthetic methodologies (such as
Houben–Weyl). Is it possible to create hyper links between these individual
information sources? |
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Pharmaceutical Substances has been developed using a framework that can potentially
allow users to integrate the program with all other online Thieme Chemistry products
at some point in the future. However, at present the cross linking software is being
developed and will not be implemented in the near future. Please visit this web site
for any future developments in product integration. |
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When searching using a substructure I obtain numerous hits that do not relate to the
compound for which I am searching. Why? |
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If you have entered a structure that contains only the carbon atom framework without
the correct bond orders the program will not recognize the fragment as a substructure
contained in your particular substance. Please ensure that all bond orders within the
fragment are correct. If the problem persists please contact us for assistance. |
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Using ISIS Draw I have entered a stereochemical representation of a structure to use in a
search query and I get no hits. Why? |
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Due to the nature of the data contained in Pharmaceutical Substances it is not possible
to search the database using stereospecific structures. Structures should be drawn
without stereochemistry to allow all the possible hits to be presented. Unfortunately,
Pharmaceutical Substances is not capable of translating 'up' and 'down' bonds into two dimensional
bonds. |
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How can I search for intermediate products in a multi step reaction scheme by drawing
a reaction in the ISIS Draw interface? |
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It is not possible to specify intermediate products within a multi-step reaction. So,
a reaction where A is the reactant, B is an intermediate product, and C is a product
is not searchable as such. It is however, possible to search for the reaction A to C,
or A to B, or B to C. |
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The reaction schemes on the screen appear to have a good resolution but when I print
them out the images seem rather pixilated. Is this normal? |
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Although the resolution of the structures contained in Pharmaceutical Substances have
been enhanced since the production of the CD-ROM edition they are still intended for
on screen viewing. As such the resolution of the printed monographs is not optimal
and is designed to be readable but not to be used for reproduction on other media. |
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When entering INN in the query list and then clicking on the index button a list of
every compound available is produced on the left hand side of the screen. However,
when I click on a name I am not taken to the compound. Why not? |
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The INN of the entry which you have clicked on now appears in the search field on
the right. If you now press the search button you will be taken straight to the relevant
monograph. |
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In the table labeled "Substances Referenced in Synthesis Path" molecular entities appear
with a molecular formula but no name or CAS-RN. Why? |
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These entities represent a molecule that may only be a transitory intermediate that is
not isolable, or it may be of undetermined structure.
As such this molecule has not been assigned a CAS-RN or a systematic name. |
