A new update to Pharmaceutical Substances was released on June 30th, 2011. The new release features 8 new active pharmaceutical ingredients and 1 updated syntheses:

Pharmaceutical Substances is compatible with Microsoft Internet Explorer 7.0 and above and Mozilla Firefox 3.0 and above (on PC's) and Safari 2.0 and above (on MAC's running OS X).

With version 3.5, Pharmaceutical Substances supports ChemDraw 9.0 and above.

You can download a detailed user manual for the built-in structure editor here.