Volume 25: Aldehydes

Introduction by Prof. Reinhard Brückner (Volume Editor):

 

This volume of Science of Synthesis concerns the synthesis of aldehydes. It covers the preparation of aliphatic and alicyclic aldehydes in the largest section, which consists of 16 subsections, and the preparation of aromatic aldehydes in the second-largest section, which is subdivided into nine subsections.

 

Three sections summarize synthetic approaches to unsaturated aldehydes, namely enals, polyenals, and ynals. The remainder of the volume is devoted to aldehydes containing heteroatoms and is organized into four sections: aldehydes with a singly bonded heteroatom at C2, aldehydes with a singly bonded heteroatom at C3, aldehydes with two singly bonded heteroatoms at C2, and aldehydes with a double bond to a heteroatom located at C2. These sections and the weight allotted to each of them are reflective of two concerns: to provide broad coverage of those types of aldehydes that are of general interest, and to compile methodology for the preparation of aldehyde classes of more specialized interest with attention to detail. The virtues of the individual methods are described and compared, many recent strategies are provided, and typical experimental procedures are included, as is usual in Science of Synthesis.

 

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