Developed in cooperation with InfoChem, Science of Synthesis possesses a user-friendly search function that allows substructure, exact structure, reaction, combined keyword, and full-text searches. Within the application, a structure search is quick and easy since users have the ability to choose between multiple structure drawing tools (ISIS Draw, Java Applet, and ChemDraw). Its compatibility with SFX assists librarians in navigating literature requests of Science of Synthesis users to resources and services relevant to their search queries.

The Advisory Board for the electronic version comprises:
A. Barth (Fachinformationszentrum Karlsruhe, Germany), G. Baysinger (Stanford University, USA), A. Mullen (Bayer AG, Germany), H. Rzepa (Imperial College, UK), and E. Zass (ETH Zurich, Switzerland).

The electronic product is designed so that it:
• Provides an exclusive overview of the synthetic chemistry literature.
• Provides easy access to the best and most reliable synthetic methods in organic and organometallic chemistry.
• Gives organic chemists examples of evaluated methodology reviewed by world-renowned experts.
• Allows researchers to tailor their structure, text and reaction searches to accommodate their chemical information needs.
• Encourages learning and understanding of complicated chemical concepts through its didactic presentation.
• Promotes the dissemination and maintenance of quality synthetic methodology information.
• Provides personalized support with scientific queries through a professionally staffed Editorial Office and Technical Support desk.
• Supports the chemical community by responding to its need for relevant and value-added synthetic chemistry information.

The current version 3.10 contains 48 volumes and over 265,000 reactions!