Science of Synthesis is continuously updated with high-quality content using clearly defined criteria for method selection as well as established editorial processes. The Editorial Board, in conjunction with the volume editors and authors, reviews the whole field of synthetic organic chemistry as presented in Science of Synthesis and evaluate significant developments in synthetic methodology.

A list of strict criteria for method selection guides the updating process in order to guarantee that only the best and most reliable synthetic methods are included in Science of Synthesis. Authors, who are renowned specialists in their respective fields, add new methods and add new (or completely revise existing) product (sub)classes.

The updating procedure is continuous and new content is added to the electronic version in four releases per year. Science of Synthesis continues to be the most up-to-date evaluated electronic reference work available, emphasizing the most significant developments in synthetic methodology.

Science of Synthesis gives convenient access to a century of synthetic organic chemistry starting with the first volume of Houben–Weyl published in 1909 right through to groundbreaking methodology added immediately upon validation by experts. The electronic version’s intuitive interface adapts in keeping with the latest technological developments and will enable chemists worldwide in both academia and industry to solve complex synthetic problems.