SYNFORM is available as part of the online editions of SYNTHESIS, SYNLETT and SYNFACTS through Thieme eJournals. This supplementary feature is available free of charge. SYNFORM presents people, trends, and views in synthetic organic chemistry with direct links to all quoted original papers. To view or download issues of SYNFORM, please click here.
Three-Component Domino Reaction Using the Bestmann Ohira Reagent: A Regioselective Synthesis of Phosphonyl Pyrazole
No one who has given even a passing glance to the literature of organic chemistry will have failed to note a flourishing development of step-economic reactions that achieve multiple bond formations in one operation. In this context, multicomponent reaction (MCR) processes usually satisfy most criteria (readily available starting reagents, atom-economical, environ - mentally friendly, etc.) required for ideal organic syntheses. Undoubtedly, such reactions offer an efficient way to generate complex molecular frameworks due to their inherent convergence and complexity-generating ability.
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