SYNFORM

SYNFORM is available as part of the online editions of SYNTHESIS, SYNLETT and SYNFACTS through Thieme eJournals. This supplementary feature is available free of charge. SYNFORM presents people, trends, and views in synthetic organic chemistry with direct links to all quoted original papers. To view or download issues of SYNFORM, please click here.

 

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First Catalytic Enantioselective Dieckmann-Type Annulation

The enantioselective synthesis of heterocycles with quaternary stereogenic centers by two consecutive catalytic C–C bond-forming processes is very demanding. Recently, the group of Dr. Christopher. G. Frost from the University of Bath (UK) described the first example of a catalytic enantioselective Dieckmann-type annulation to form pyrrolidines with quaternary stereogenic centers (up to 98:2 er).

 

To read more please download SYNFORM 2010/06 online, free of charge.

Posted By: Matteo Zanda on May 21, 2010 12:03PM Add Comment
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